Herantis Pharma Plc ("Herantis" or "Company") announced today the topline results from the ongoing Phase 1-2 clinical trial examining Herantis' proprietary neuroprotective factor and novel drug candidate, CDNF, in patients with Parkinson's disease.

Herantis Pharma Oyj: Herantiksen CDNF on turvallinen ja hyvin siedetty Vaiheen 1-2 tutkimuksessa 12 kuukauden hoidon jälkeen. Publicerad: 2020-08-27 (Cision) Herantis Pharma Oyj: Herantis Pharma Plc Announces CDNF Phase I-II Study Met Primary Endpoints of Safety and Tolerability at 12 months. Publicerad: 2020-08-27 (Cision)

Both CDNF and xCDNF have, via their multimodal mechanism of action, the potential improves neuronal survival and to stop the progression of Parkinson’s and other CDNF - a biological protein - is Herantis' lead program and a clinical stage asset; and xCDNF - a synthetic peptide version of CDNF - is Herantis' follow-on program. Both CDNF and xCDNF have, via their multimodal mechanism of action, the potential improves neuronal survival and to stop the progression of Parkinson's and other neurodegenerative disease and have a significant therapeutic impact on the lives of patients. Herantis Pharma has announced that its novel drug candidate, Cerebral Dopamine Neurotrophic Factor (CDNF) for the treatment of Parkinson’s disease (PD), has successfully achieved its primary endpoint of safety and tolerability in a 12 month Phase I-II study in patients with moderate disease. Based on internationally recognized science, Herantis’ drug development pipeline targets breakthroughs in diseases with unmet clinical need. We aim to develop our products through clinical proof-of-concept and, where considered appropriate, to partner with large pharmaceutical or biotech companies for late-stage development and commercialization.

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Herantis Pharma meddelar att toplinedata från bolagets fas I-II-studie med kandidaten CDNF för behandling av patienter med Parkinsons  2020-08-27 08:00:00 Herantis Pharma Herantis Pharma Oyj: Herantiksen CDNF on turvallinen ja hyvin siedetty Vaiheen 1-2 tutkimuksessa 12  6 April, 17:00. DI - 2020-12-17 18:15:14. Nanoform and Herantis partner to look for opportunities to enhance BBB penetration of CDNF and xCDNF molecules  of Herantis' CDNF therapies for Parkinson's disease using Nanoform's proprietary biological nanoparticle technology. As a result, Nanoform  Herantis Pharma meddelade att en behandling som kallas cerebral dopamin neurotrofisk faktor (CDNF) har beviljats särläkemedelsstatus av  Teknisk analys Herantis Pharma (HRNTS).

29/03/2016.

Läkemedelsbolaget Herantis Pharma Plc är tillsammans med företaget av del studieläkemedlet CDNF vid långtidsbehandling av Parkinsons sjukdom.

Key assets include CDNF for Parkinson’s disease and Lymfactin for breast cancer associated lymphedema. 2021-03-11 Herantis Pharma Plc Company release, insider information 25 February 2020 at 9:00 AM Eastern European Time.

2021-03-10

Both CDNF and xCDNF have, via their multimodal mechanism of action, the potential improves neuronal survival and to stop the progression of Parkinson's and other neurodegenerative disease and have a significant therapeutic impact on the lives of patients.

CDNF on Herantiksen yksinoikeudella kehittämä, hermosoluja suojaava lääkeaihio, jonka tavoitteena on muuttaa Parkinsonin taudinkulkua, mikä olisi merkittävä läpimurto verrattuna tunnettuihin In order to do this, Herantis has developed xCDNF, a patented, chemically synthesised form of CDNF that uses small but potent biologically active fragments of the parent CDNF molecule, which it says can reach the key areas of the brain in therapeutic concentrations using a simple dosing method such as subcutaneous injection. Herantis Pharma is focused on the development of innovative regenerative medicines targeting unmet needs. The recent virtual capital markets day highlighted the progress of its two innovative assets: cerebral dopamine neurotrophic factor (CDNF), a potential disease-modifying treatment for Parkinsonâ s disease (PD); and Lymfactin, the only gene therapy in development for breast cancer Herantis Pharma is a Finnish innovative biopharmaceutical company focusing on regenerative medicines for unmet needs. Key assets include CDNF for Parkinson’s disease and Lymfactin for breast cancer associated lymphedema.
Retorik

2017-09-27 · Herantis Pharma has initiated patient recruitment and consented first patient in CDNF study in Parkinson's disease. Herantis Pharma Plc Company release 27 Sep 2017 at 9:00 am Herantis Pharma är ett forskningsbolag. Idag innehas särskilt fokus mot behandling av ett flertal sjukdomar som Parkinsons sjukdom, skleros samt bröstcancer. Bolaget innehar en produktportfölj som för närvarande befinner sig i diverse kliniska faser. 2020-02-25 · Source: Herantis It is cold this time of year in Helsinki, but there will be some warm smiles there today.

Intracerebral delivery abandonedMore patient friendly methods to be exploredA fresh start with an accelerated development trajectoryIntracerebral delivery deeme Herantis Pharma Plc. Company release, Inside Information 29 March 2021 at 9:00 PM EET. Herantis Pharma Plc ("Herantis or the Company"), an innovative clinical stage biotech company pioneering new disease modifying and regenerative therapies, today announced that the Board of Directors has decided to focus all company resources on Herantis' CDNF and xCDNF assets and to commence seeking out “ CDNF is now one of a few clinical stage assets in development with the potential for disease modification of Parkinson’s Disease. The intranasal administration route of CDNF is an important program for Herantis to maximize the chances of success for CDNF in brain disorders.
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Herantis Pharma Plc (“Herantis”), an innovativeclinical stage CDNF biological therapy that acts on the proteostatic mechanisms of disease for 

CDNF, or Cerebral  Herantis Pharma Plc Announces Topline Results of Phase 1-2 CDNF Trial. 2/25/ 2020. HELSINKI , Feb. 25, 2020 /PRNewswire/ -- Topline analysis confirms  18 May 2020 20. joulukuu 2019 27 Feb 2020 Renishaw and Herantis Pharma's clinical study's repeated delivery as patients receive ongoing monthly infusions of CDNF using the device. 18 Dec 2019 The regenerative medicine drug candidates of Herantis Pharma, CDNF and Lymfactin®, aim to revolutionise the treatment of Parkinson's  15 Mar 2018 The cerebral dopamine neurotrophic factor (CDNF) is a promising a CDNF- related patent application that is owned by Herantis Pharma Plc. 16 Oct 2017 In addition to CDNF, Herantis Pharma is developing the drug candidate Lymfactin® for the treatment of breast cancer associated lymphedema.